Development and Optimization of Solid Lipid Nanoparticle for Topical Delivery
نویسندگان
چکیده
منابع مشابه
Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a Box-Behnken design
The purpose of the present study was to optimize a solid lipid nanoparticle (SLN) of chloramphenicol by investigating the relationship between design factors and experimental data using response surface methodology. A Box-Behnken design was constructed using solid lipid (X(1)), surfactant (X(2)), and drug/lipid ratio (X(3)) level as independent factors. SLN was successfully prepared by a modifi...
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Solid lipid nanoparticle (SLN) delivery systems have a wide applicability in the delivery of phyto-bioactive compounds to treat various chronic diseases, including diabetes, cancer, obesity and neurodegenerative diseases. The multiple benefits of SLN delivery include improved stability, smaller particle size, leaching prevention and enhanced lymphatic uptake of the bioactive compounds through o...
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Delivering the drug accurately and safely to its target site at the precise time period to have a controlled release and attain the maximum therapeutic effect remains a benchmark in the design and development of newer drug delivery systems. In this review, the latest research developments of the Solid lipid nanoparticles (SLNs) according to the recent relevant literatures were focussed. This pa...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2019
ISSN: 2250-1177
DOI: 10.22270/jddt.v9i5-s.3648